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Gonge G-2117 Tactile Discs, Multicolour

£41.495£82.99Clearance
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Blake DT, Johnson KO, Hsiao SS (1997) Monkey cutaneous SAI and RA responses to raised and depressed scanned patterns: effects of width, height, orientation, and a raised surround. J Neurophysiol 78:2503–2517

Johansson RS, Flanagan JR (2009) Coding and use of tactile signals from the fingertips in object manipulation tasks. Nat Rev Neurosci 10:345–359 Khalsa PS, Friedman RM, Srinivasan MA, Lamotte RH (1998) Encoding of shape and orientation of objects indented into the monkey fingerpad by populations of slowly and rapidly adapting mechanoreceptors. J Neurophysiol 79:3238–3251

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Press D, Mutlu S, Guclu B (2010) Evidence of fast serotonin transmission in frog slowly adapting type 1 responses. Somatosens Mot Res 27:174–185 Kautio AL, Haanpaa M, Kautiainen H, Kalso E, Saarto T (2011) Burden of chemotherapy-induced neuropathy – a cross-sectional study. Support Care Cancer 19:1991–1996 Rao RD, Michalak JC, Sloan JA, Loprinzi CL, Soori GS et al (2007) Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled, crossover trial (N00C3). Cancer 110:2110–2118

Findlater GS, Cooksey EJ, Anand A, Paintal AS, Iggo A (1987) The effects of hypoxia on slowly adapting type I (SAI) cutaneous mechanoreceptors in the cat and rat. Somatosens Res 5:1–17 Albers J, Chaudhry V, Cavaletti G, Donehower R (2007) Interventions for preventing neuropathy caused by cisplatin and related compounds. Cochrane Database Syst Rev 24:CD005228 Baumann KI, Chan E, Halata Z, Senok SS, Yung WH (1996) An isolated rat vibrissal preparation with stable responses of slowly adapting mechanoreceptors. Neurosci Lett 213:1–4 Bosman LW, Houweling AR, Owens CB, Tanke N, Shevchouk OT et al (2011) Anatomical pathways involved in generating and sensing rhythmic whisker movements. Front Integr Neurosci 5:53A mechanoreceptor is a sensory receptor that responds to mechanical pressure or distortion. For instance, in the periodontal ligament, there are mechanoreceptors that allow the jaw to relax when biting down on hard objects; the mesencephalic nucleus is responsible for this reflex. Basbaum AI, Bautista DM, Scherrer G, Julius D (2009) Cellular and molecular mechanisms of pain. Cell 139:267–284

Haeberle H, Fujiwara M, Chuang J, Medina MM, Panditrao MV et al (2004) Molecular profiling reveals synaptic release machinery in Merkel cells. Proc Natl Acad Sci U S A 101:14503–14508 Mills LR, Diamond J (1995) Merkel cells are not the mechanosensory transducers in the touch dome of the rat. J Neurocytol 24:117–134 FUN MATCHING GAME: With little matching circular toys prepared for the large discs, they feature the similar textured surfaces, pairing them together by feet can be challenging and fun when blindfolded (Eye mask included). receptive field: The particular region of the sensory space (e.g., the body surface, space inside the ear) in which a stimulus will trigger the firing of that neuron. Hama A, Takamatsu H (2016) Chemotherapy-induced peripheral neuropathic pain and rodent models. CNS Neurol Disord Drug Targets 15:7–19

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Chang W, Kanda H, Ikeda R, Ling J, DeBerry JJ, Gu JG (2016) Merkel disc is a serotonergic synapse in the epidermis for transmitting tactile signals in mammals. Proc Natl Acad Sci U S A 113:E5491–E5500 Ikeda R, Cha M, Ling J, Jia Z, Coyle D, Gu JG (2014) Merkel cells transduce and encode tactile stimuli to drive Abeta-afferent impulses. Cell 157:664–675 Zimmerman A, Bai L, Ginty DD (2014) The gentle touch receptors of mammalian skin. Science 346:950–954 Bymaster FP, Beedle EE, Findlay J, Gallagher PT, Krushinski JH et al (2003) Duloxetine (Cymbalta), a dual inhibitor of serotonin and norepinephrine reuptake. Bioorg Med Chem Lett 13:4477–4480 Huang M, Chalfie M (1994) Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans. Nature 367:467–470

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