To a solution of 3,5-dimethylaniline (3.0 ml, 24 mmol) in ice cold dichloromethane (200 ml) was added trifluoroacetic anhydride (4.18mL, 1.25 equivs). After 30 minutes, bromine (1.2 ml, 0.97 equivs) was slowly added over 5 minutes. After aqueous work-up and drying in vacuo the recovered crude (6.81 g, 96percent) was taken up in dry THF (40 ml). The solution was cooled to -78 0C and methyl lithium'lithium bromide complex (21 ml, 1.3 equivs) was added. After 5 minutes, s-butyllithium (20 ml, 1.3 equivs) was added followed by di-t-butyldicarbonate (8.02 g, 1.6 equivs). Following aqueous work up the crude amide was taken up in a 3:1 solution of methanol: water (100 ml) followed by sodium hydroxide (5 ml, 1OM, 2 equivs). The reaction was stirred at 6O 0C overnight. Solvent was removed and the crude was diluted with dichloromethane, washed with water, brine, and dried over sodium sulfate. The aniline was then taken up in dichloromethane (2 ml) and n-propylisocyanate (74 μL, 1.2 equivs). After two hours, solvent was removed and the crude residue was taken up in HCl/ethanol solution (1.2M, 15 ml) and stirred at 50 °C overnight. After solvent was removed, the crude 2,6-dimethyl-4-(3- propyl-ureido)-benzoic acid was isolated as a white solid (94 mg).[0425] 1H NMR (CDCl 3) δ 0.83-0.99 (m, 7H), 1.02-1.11 (m, IH), 1.46-1.77 (m, 8H), 2.11 (s, 6H), 2.48-2.57 (m, IH), 1.66-1.82 (m, 3H), 3.12-3.22 (m, 3H), 3.52-3.20 (m, 4H), 3.75-3.82- 3.90 (m, IH), 4.11-4.25 (m, IH), 5.67-5.75 (m, IH), 6.61 (s, 2H), 6.89 (d, IH, J= 6 Hz), 7.03 (s, IH), 7.22 (s, IH), 7.27-7.32 (m, IH), 7.48 (s, IH), 8.87 (br s, IH); ES-MS m/z 573 (M+H).

What is 90 divided by 3/4? - Divisible

Interim manager Ryan Mason will surely have warned his players about the perils of such a hesitant opening and yet they played the opening 15 minutes as if they were in a daze. Dea makes 18 out of 27 shots in a basketball game. Which decimal represents the fraction of shots Dea makes? Payusing your mobile– Location Number: 712004 -For more information call:0345 520 7007or visit www.mipermit.com/help To a solution of copper(I) chloride (26.0 g, 0.250 mmol) in water (7.5 mL) was added dropwise thionyl chloride (1.3 mL) under ice-cooling, then the reaction temperature was gradually elevated, and the mixture was stirred at room temperature overnight. (1-B) [0408] To a mixture of [59557-90-3]3,5-dimethyl-4-bromoaniline (500 mg, 2.499 mmol) in concentrated hydrochloric acid (2.5 mL) and water (0.5 mL) was added dropwise a solution of sodium nitrite (193 mg, 2.749 mmol) in water (1.3 mL) at -5C. After stirred at -5C for 30 minutes, to the mixture was added dropwise a solution prepared in (1-A) at the same temperature. The reaction temperature was gradually elevated, and the reaction mixture was stirred at room temperature overnight. The reaction mixture was extracted three times with chloroform, the organic layer was combined, dried, and concentrated under reduced pressure to give a crude product of 4-bromo-3,5-dimethylbenzenesulfonyl chloride (375 mg). The resultant was used in the next step without further purification Liverpool are right in the fight for a place in Europe as they overhauled Spurs, but this was a performance that demonstrated once again the two sides to their game they have shown throughout this season. Spurs pay for slow start againreducing or simplifying the fraction (simplification) : 4/22 - dividing the numerator and denominator of a fraction by the same non-zero number - equivalent fraction First, 3,5-dimethyl aniline (10.0 g, 82.5 mmol) was dissolved in MeCN. NBS (15.4 g, 86.6 mmol) was added and the reaction mixture was stirred for two days at room temperature. IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. So now that we've converted 90 into a fraction, to work out the answer, we put the fraction 3/4 side by side with our new fraction, 90/1 so that we can multiply those two fractions. Rules for expressions with fractions: Fractions - use a forward slash to divide the numerator by the denominator, i.e., for five-hundredths, enter 5/100. If you use mixed numbers, leave a space between the whole and fraction parts.

Inches to Cm Converter - The Calculator Site Inches to Cm Converter - The Calculator Site

IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. Flow control valves, centering bushings, O-rings for direct connection, fitting screws (SRU-plus 63 only), assembly and operating manual with manufacturer’s declaration To a solution of 3,5-dimethyl-phenylamine (400 mg) in THF (35 mL) was added n-BuLi (1.45 mL, 2.5 M solution in hexane) at -78 C. The mixture was stirred at -78 C. for 20 min, allowed to warm up to -40 C. for 5 min, and then was cooled down to -78 C. again. After 10 min, B(OMe)3 (0.4 mL) was added dropwise. The mixture was stirred at -78 C. for 2.5 h, warmed up to 10 C. slowly, and then was cooled down to -78 C. again. Bromine (0.185 mL) was added dropwise to the mixture. The mixture was stirred at -78 C. for 1.5 h, and allowed to warm up to 0 C. for 1 h. The reaction was quenched with saturated NaHCO3 aqueous solution and 20% Na2S2O3 aqueous solution. The aqueous layer was extracted with EtOAc, and the organic extracts were washed with brine, dried over Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography (SiO2, EtOAc:Hexane=5:95 to 40:60) to give 4-bromo-3,5-dimethyl-phenylamine as a white solid: MS (m/z) 200 (M+1); 1H NMR (CDCl3, 400 MHz) delta 6.43 (s, 2H), 3.52 (s, 2H), 2.31 (s, 6H).

In this case, our new fraction can actually be simplified down further. To do that, we need to find the greatest common factor of both numbers. With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; potassium carbonate; In N,N-dimethyl-formamide; at 90℃; for 1h; Analysis by TLC and HPLC indicated that in addition to the desired product several side products had been formed (regio-isomers and di-brominated side products). What is 3/4 of 90?. VisualFractions.com. Retrieved from http://visualfractions.com/calculator/fraction-of-number/what-is-3-4-of-90/. Tottenham's season has been characterised by slow starts and they paid the price once more for failing to get to grips with the game in the opening phase.

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Former England goalkeeper Karen Bardsley says action is needed to keep the close connection between fans and players. To a mixture of cyclopentanone (42 mg, 0.500 mmol) and [59557-90-3]4-bromo-3,5-dimethylaniline (100 mg, 0.500 mmol) in acetic acid (0.5 mL), trimethylsilyl cyanide (0.063 ml, 0.500 mmol) was added at room temperature. The mixture was stirred at room temperature for 1.5 hours under nitrogen atmosphere. The reaction mixture was quenched with 28% aqueous ammonia (1 mL), diluted with water and extracted with dichloromethane. The organic layer was washed with water and brine, dried over anhydrous sodium sulfate, and then concentrated under reduced pressure to afford 1-((4-bromo-3,5-dimethylphenyl)amino)cyclopentanecarbonitrile as a crude product (152 mg). 1H-NMR (400MHz, CDCl3) delta: 1.83-1.92 (4H, m), 2.07-2.15 (2H, m), 2.33-2.42 (2H, m), 2.37 (6H, m), 3.71 (1H, brs), 6.56 (2H, s) Because slash is both sign for fraction line and division, use a colon (:) as the operator of division fractions i.e., 1/2 : 1/3. Next, we will subtract the result from the previous step from the third digit of the dividend (0 - 0 = 0) and write that answer below: To a solution of [59557-90-3]4-bromo-3,5-dimethylaniline (3.47 g, 17.4 mmol) and diisopropylethylamine (5.3 mL, 30.4 mmol) in DMI (13 mL), 2-bromoisobutyric acid (3.86 g, 23.1 mmol) was added at room temperature. The mixture was stirred at 100C for one hour. And then 2-bromoisobutyrate (496 mg, 2.97 mmol) and diisopropylethylamine (0.8 mL, 4.59 mmol) was added and the mixture was stirred at 100C for one hour. Methanol (52 mL) and a 5 N aqueous sodium hydroxide solution (52 mL, 260 mmol) were added to the reaction mixture at room temperature, and then this mixture was stirred at 75C for 1.5 hours. The reaction mixture was cooled, followed by addition of water and adjustment of the pH to 5 using a 1 N aqueous potassium hydrogen sulfate solution, and then extracted using ethyl acetate. The organic layer was washed with water, then dried over anhydrous magnesium sulfate, and concentrated to yield 2-((4-bromo-3,5-dimethylphenyl)amino)-2-methyl propanoic acid as a crude product (5.79 g). MS(ESI) m/z = 286,288 (M+H)+

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Here, you will find our full range of brass and stainless steel hosetails and hose joiners. All available in a variety of British Standard Pipe (BSP) threads and metric sizes. Please note that the final angular degrees (approx. 2°) before the end position can only be approached using the force of a single drive piston. For this reason, double actuated modules only have about half the rated torque available in this area. An external stop can be used to provide the full torque even in the end positions. is the rotation time of pinion/flange around the nominal rotation angle. Valve switching times, hose filling times, or PLC reaction times are not included and are to be considered when cycle times are calculated. The worst example was in that 6-1 debacle on Tyneside a week ago, and they looked on course for a repeat here as Liverpool took advantage of Spurs sleepwalking once again to race into that early lead. If we multiply the divisor by the result in the previous step (3 x 0 = 0), we can now add that answer below the dividend: