So, many vets now recommend using a harness instead of a collar to protect the dog’s throat and thyroid glands.

Dog Bone Ball Gag PetPlay Puppy Play Fetish Kink | DDLG

We try to keep a consistent supply of colours, but some items may differ slightly in shade from those shown in product photos. It is important to note that unlike proteins and nucleic acids, GAG biosynthesis is a non-template driven process that occurs through the combined action of several tissue-specific enzymes.Just put them in warm water with soap (antibacterial if possible) and use a piece of cloth to gently clean every bit of saliva left on them. Please refer to our page on kennel cough for more information on the symptoms and treatment of this disease. The tethering process for the GAGs heparin/heparan sulfate, chondroitin sulfate, and dermatan sulfate occurs through a serine amino acid residue present on the protein core that connects to a common tetrasaccharide linker between the GAG and PG. Here at DDLG Playground we are passionate about cute, kinky, and kawaii fashion surrounding the DDLG / CGL / ABDL / BDSM and littlespace communities! If a dog is suffering from kennel cough, he will have a dry, hacking cough, which is often accompanied by gagging and retching.

Bone Gag – Leather Delights

Variations in the type of monosaccharides and the presence or absence of modification by sulfation results in the different major categories of GAGs, including hyaluronic acid, heparin/heparan sulfate, chondroitin sulfate/dermatan sulfate, and keratan sulfate. Rhinitis (nasal infection) and sinusitis (sinus infection) can cause dog gagging or retching (from a postnasal drip), sneezing, and nasal discharge. GAGs are very important to the infectious processes of various viral, bacterial, fungal, and parasitic pathogens.

This cheeky 100% vegan puppy or dog bone collar / gag is perfect for kinky cuties who like to embody their inner canine! The availability of PAPS for sulfation of GAGs significantly affects the biosynthetic rate of production of sulfated GAGs [4].